Montelukast (Singulair) and Urticaria

September 30, 2008

Montelukast is an antiasthmatic drug used to control chronic asthma and help decrease the number of asthma attacks. It is also used to treat hay fever.

Many patients’ chronic hives (urticaria) are not sufficiently controlled with histamine blockers. Researchers in Japan studied the effectiveness of montelukast for the treatment of chronic urticaria. Twenty-five patients were treated with Singulair for one week or more, without changing any treatment that they were using before the study, including histamine blockers. Twelve people, including six who had been treated with corticosteroids, were evaluated as “markedly improved” or “improved” following treatment with montelukast. Researchers concluded that montelukast may be worth trying for patients with chronic urticaria, when the condition is not sufficiently controlled with histamine blockers.

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